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The Science Behind Liquid Biocell

Liquid BioCell

Types of Modere Liquid Biocell

Liquid Biocell Life – Liquid Biocell Life is a super nutraceutical made with award-winning Liquid BioCell®, a natural source of type II collagen, a material produced naturally in the body’s articular cartilage that nourishes and supports active and ageing joints.

Liquid Biocell Pure – Liquid Biocell Pure is a supernutritional that combines award-winning Liquid BioCell®, a clinically validated chemical that promotes healthy aging, active joints, and younger-looking skin.

Liquid BioCell Skin – You can now drink your skincare with Liquid BioCell Skin, a sophisticated nutricosmetic that is professionally formulated with Liquid BioCell®, a component proven to combat wrinkles from the inside out while reducing hyaluronidase, the enzyme that causes your skin to age.

Liquid Biocell Sport — Liquid BioCell Sport is a revolutionary Bio-Optimized blend that can help you achieve your performance goals.
It contains ingredients that enhance recovery, increase joint and muscle health, and fuel physical and mental performance.

Liquid Biocell Pet — Liquid BioCell Pet delivers healthy collagen, hyaluronic acid, and chondroitin sulfate to active and geriatric dogs and cats.

Liquid Biocell Equine — Liquid BioCell Equine is a cutting-edge nutraceutical that provides healthy joint support for horses of all breeds.

It uses Collagen/HA Matrix® Technology in our advanced liquid delivery system to keep the horse’s joints mobile and functional while also maintaining a healthy coat.

About Modere

MODERE COLLAGEN SCIENCES is the creator of Liquid BioCellTM and is a division of MODERE.

The Ivy League-educated scientific team at Modere Collagen Sciences controls a 150,000-square-foot manufacturing and product development facility that complies with the US Food and Drug Administration’s Current Good Manufacturing Practice criteria (FDA).

The cutting-edge product line is based on the Liquid BioCellTM formulation, a one-of-a-kind product that combats aging and joint damage from the inside out.
The medicine, which is backed by 37 clinical trials and seven U.S. and international patents, has been shown to work for both humans and pets.

Liquid BioCell Life Before and After

Liquid BioCell is a naturally derived Collagen/HA Matrix that’s scientifically tested and backed by 7 U.S. and international patents. What makes it so unusual? This award-winning, single-source matrix combines highly absorbable collagen with hyaluronic acid and chondroitin sulfate, in concentrations that mirror human articular cartilage composition. It’s clinically shown to deliver remarkable joint benefits—and dramatic skin benefits too.*

Collagen as a nutritional ingredient
can be classified into one of several groups depending on its type, source and manufacturing processes. The most common varieties of collagen are:

(includes trendy bone
broth supplements)Hydrolyzed, derived from porcine skin/bovine hide (aka gelatin), eggshell membrane and/or fish

(made from chicken
sternal cartilage)Undenatured or unhydrolyzed collagenORHydrolyzed collagen matrix: a natural matrix of collagen, hyaluronic acid and chondroitin sulfate (Liquid BioCell®)

The Features

*When used as directed.The innovations pioneered by Liquid BioCell, such as our advanced liquid delivery system, have set new precedents in the industry that continue to challenge conventional brands to step up their game. However, none can match the unique combination of single-source collagen, the matrix composition and optimal molecular weight that makes Liquid BioCell so effective. Only Liquid BioCell offers all of the following features:

  • Mutiple Industry awards
  • 7 U.S. and international patents
  • Naturally sourced matrix (not a blend) consiting of hydrolyzed type II collagen (60%)hyaluronic acid (10%)chondroitin sulfate (20%)
  • Patented Colagen/HA Matrix mirrors natural articular cartilage
  • Patented Bio-Optimized process results in the ideal molecular weight for enhanced absorption
  • Liquid delivery system
  • Concentrated formula

The Clinical Benefits

As the gold standard for supplemental collagen since its launch, Liquid BioCell has inspired groundbreaking trends that have since been attempted by other brands, like a collagen matrix ingredient. Even so, Liquid BioCell (Hydrolyzed collagen matrix) still stands alone in delivering all of these clinically demonstrated benefits:

  • Clinically shown to support joint and connective tissue health*
  • Improvement in joint discomfort and physical activity after 8 weeks*
  • Substantiated benefits for youthful skin*May stimulate the body to produce new collagen
  • Increased HA levels in blood by 6000% after 28 days
  • Dramatically reduced skin dryness/scaling after 12 weeks
  • Clinically shown to inhibit hyaluronidase, the enzyme that degrades HA and causes skin aging
  • Measurably reduced wrinkles and deep lines after 12 weeks


While there are many different types of collagen in the body, type II is predominant in human articular cartilage—the specialized connective tissue responsible for smooth, active joint movement. More specifically, human joints are largely composed of type II collagen, hyaluronic acid and chondroitin sulfate, and each of these serves an important role in the healthy function of joints.

In the simplest terms, collagen is a major component of healthy joints, youthful skin and connective tissue. Hyaluronic acid is essential to skin hydration, tissue maintenance and a youthful appearance. And chondroitin sulfate supports joint flexibility and lubrication.

Liquid BioCell features all three of these vital substances in a naturally derived, single-source matrix. Backed by multi-patented Collagen/HA Matrix® Technology, this proprietary ingredient largely mirrors human articular cartilage composition and is hydrolyzed using a patented Bio-Optimized™ manufacturing process to achieve an ideal molecular weight. The result is naturally enhanced bioavailability. Bioavailability has a direct bearing on how beneficial a supplement is, because it measures how efficiently a substance enters a body’s circulatory system. Ingesting a nutrient is not enough; it must be absorbed in order to derive any benefit, so the bioavailability of a supplement can be just as important as, if not more so than, what its nutrition label may claim.


Given these facts, it’s no surprise that Liquid BioCell is clinically demonstrated to improve joint mobility, promote healthy cartilage and connective tissue, and support joint lubrication. In fact, a double-blind, placebo-controlled trial of Liquid BioCell revealed measurable improvement in joint discomfort over 8 weeks, and many subjects experienced significant mobility with continued use.

What’s more, a recent finding suggests that hydrolyzed collagen in Liquid BioCell may directly activate chondrocytes (cartilage cells) to stimulate the body to produce its own new collagen.

Restores Youthful Skin, Increasing Collagen and HA

Collagen, hyaluronic acid and chondroitin are essential to healthy skin too. But with advancing age, the natural decline of these substances leads to the gradual loss not only of joint comfort and mobility, but skin hydration, firmness and elasticity too. Environmental stress and photoaging can accelerate this loss.

While many collagen products claim to benefit skin, few include the added benefits of hyaluronic acid and chondroitin sulfate, along with a remarkably low molecular weight to optimize bioavailability. Liquid BioCell’s patented matrix effectively replenishes these vital substances, delivering collagen to promote firmer, younger-looking skin, HA to hydrate and plump wrinkles and chondroitin sulfate to support healthy skin. But the benefits don’t stop there.

Liquid BioCell actually helps increase the body’s natural HA levels too. A human bioavailability study demonstrated that daily intake of this collagen/HA matrix led to a 60-fold increase of HA in the body after just 28 days. That’s an astounding 6000%!

Eliminates Skin Dryness Without Topical Moisturizers

Hyaluronic acid molecules possess the remarkable ability to hold 1000 times their own weight in water, so it’s no wonder that HA plays a role in skin hydration, density and volume. In a 12-week study of subjects taking Liquid BioCell®, skin dryness/scaling nearly disappeared without the use of topical moisturizers. They also experienced enhanced microcirculation and a significant increase in skin’s collagen content, visibly reducing wrinkles and deep lines from the inside out.


Inhibits the Enzyme That Causes Skin Aging

Additionally, research has shown a noticeable reduction in levels of hyaluronidase—the enzyme that degrades HA and accelerates aging—among subjects taking Liquid BioCell. That is, Liquid BioCell can slow the natural loss of hyaluronic acid. The result is radiant-looking skin that appears younger, longer.

Clinically Proven Anti-Aging Formulation

Skin Dryness and Scaling

Facial dryness and scaling may be associated with the water content in the skin and the skin aging process. Skin dryness or scaling was measured using visual/tactile scores; its mean value at week 12 decreased significantly by 76% (P = 0.002) from the baseline level, suggesting that BCC ingestion reduces skin dryness and scaling (Schwartz).



Clinically Proven Anti-Aging Formulation

Reduction of Global Facial Lines and Wrinkles

Skin aging in the face culminates with the appearance of visible signs such as wrinkles and lines. Measurement of these aging signs using visual/tactile scores showed that 12 weeks of supplementation with BCC led to significant improvement of facial lines and wrinkles with an average reduction of 13.2% (P = 0.028) from baseline (Schwartz).  

An initial increase was noted at week 6 (22.4%, P < 0.001). Another facial aging sign, crow’s feet, displayed a similar trend with a significant increase during the first 6-week period (50.7%), followed by a significant decrease (−30.4%) in visible aging signs between weeks 6 and 12 (Schwartz).  

Unlike facial lines and wrinkles, however, crow’s feet were not affected significantly by the end of study compared to the baseline level.

Skin Dryness and Scaling


(awarded for Modere Logiq™)
Beauty Shortlist Mama & Baby Awards, 2019

(awarded for Trim)
SupplySide West Editor’s Choice, 2018

(awarded for Trim)
DSA Awards, 2018

TasteForLife Supplement Essentials, 2015

SupplySide West CPG Editor’s Choice, 2015

Nutraingredients Awards Winner, 2015

Remedies Magazine, 2015

Nutraceutical Business & Technology Award, 2012

Frost & Sullivan Award Winner, 2011


Beauty From Within Conference, 2011

See the Proof:

See what Liquid BioCell® has done for real people who took the daily recommended does for 12 weeks†, and then see what it can do for you.

Work Cited

Schwartz, S R.  “Ingestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs.”

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